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Hepatocyte-Specific Knock-Out of Nfib Aggravates Hepatocellular Tumorigenesis via Enhancing Urea Cycle

Nuclear Factor I B (NFIB) has been reported to promote tumor growth, metastasis, and liver regeneration, but its mechanism in liver cancer is not fully elucidated. The present study aims to reveal the role of NFIB in hepatocellular carcinogenesis. In our study, we constructed hepatocyte-specific NFI...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Wang, Qing-Liang, Mao, Lin-Hong, Chen, Si-Yuan, Yang, Zi-Han, Liu, Xue, Gao, Yu-Hua, Li, Xiao-Qin, Zhou, Zhi-Hang, He, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152321/
https://www.ncbi.nlm.nih.gov/pubmed/35655758
http://dx.doi.org/10.3389/fmolb.2022.875324