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Intranasal Delivery of Recombinant S100A8 Protein Delays Lung Cancer Growth by Remodeling the Lung Immune Microenvironment

Lung cancer is the leading cause of cancer-related death worldwide. Increasing evidence indicates a critical role for chronic inflammation in lung carcinogenesis. S100A8 is a protein with reported pro- and anti-inflammatory functions. It is highly expressed in myeloid-derived suppressor cells (MDSC)...

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Detalles Bibliográficos
Autores principales: Wong, Sze Wing, McCarroll, Joshua, Hsu, Kenneth, Geczy, Carolyn L., Tedla, Nicodemus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152328/
https://www.ncbi.nlm.nih.gov/pubmed/35655772
http://dx.doi.org/10.3389/fimmu.2022.826391