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Proficiency of Extracellular Vesicles From hiPSC-Derived Neural Stem Cells in Modulating Proinflammatory Human Microglia: Role of Pentraxin-3 and miRNA-21-5p

Extracellular vesicles (EVs) shed by human-induced pluripotent stem cell (hiPSC)-derived neural stem cells (hNSC-EVs) have shown potent antiinflammatory properties in a mouse macrophage assay and a mouse model of acute neuroinflammation. They can also quickly permeate the entire brain after intranas...

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Detalles Bibliográficos
Autores principales: Upadhya, Raghavendra, Madhu, Leelavathi N., Rao, Shama, Shetty, Ashok K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152457/
https://www.ncbi.nlm.nih.gov/pubmed/35656007
http://dx.doi.org/10.3389/fnmol.2022.845542