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Effect of Bone Morphogenetic Protein-2 (BMP-2)/Hydroxyapatite/In Situ-Formed Hyaluronan Hydrogel Composites on Bone Formation in a Murine Model of Posterolateral Lumbar Fusion

Several types of calcium phosphate (CaP) biomaterial carriers have been designed to deliver bone morphogenetic protein-2 (BMP-2) to augment spinal fusion in spinal surgery. Here, we evaluated an in situ-formed hydrogel (IFH) constructed from hyaluronan (IFH-HA) combined with a BMP2/hydroxyapatite (H...

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Detalles Bibliográficos
Autores principales: Kuroda, Akiyoshi, Saito, Wataru, Inoue, Gen, Miyagi, Masayuki, Shoji, Shintaro, Sekiguchi, Hiroyuki, Takaso, Masashi, Uchida, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152467/
https://www.ncbi.nlm.nih.gov/pubmed/35663656
http://dx.doi.org/10.7759/cureus.25509