Inhibition of VRK1 suppresses proliferation and migration of vascular smooth muscle cells and intima hyperplasia after injury via mTORC1/β-catenin axis

Characterized by abnormal proliferation and migration of vascular smooth muscle cells (VSMCs), neointima hyperplasia is a hallmark of vascular restenosis after percutaneous vascular interventions. Vaccinia-related kinase 1 (VRK1) is a stress adaption-associated ser/thr protein kinase that can induce...

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Detalles Bibliográficos
Autores principales: Sun, Xiongshan, Zhao, Weiwei, Wang, Qiang, Zhao, Jiaqi, Yang, Dachun, Yang, Yongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152580/
https://www.ncbi.nlm.nih.gov/pubmed/35410639
http://dx.doi.org/10.5483/BMBRep.2022.55.5.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152580/
https://www.ncbi.nlm.nih.gov/pubmed/35410639
http://dx.doi.org/10.5483/BMBRep.2022.55.5.019

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