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Inhibition of VRK1 suppresses proliferation and migration of vascular smooth muscle cells and intima hyperplasia after injury via mTORC1/β-catenin axis
Characterized by abnormal proliferation and migration of vascular smooth muscle cells (VSMCs), neointima hyperplasia is a hallmark of vascular restenosis after percutaneous vascular interventions. Vaccinia-related kinase 1 (VRK1) is a stress adaption-associated ser/thr protein kinase that can induce...
Autores principales: | Sun, Xiongshan, Zhao, Weiwei, Wang, Qiang, Zhao, Jiaqi, Yang, Dachun, Yang, Yongjian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152580/ https://www.ncbi.nlm.nih.gov/pubmed/35410639 http://dx.doi.org/10.5483/BMBRep.2022.55.5.019 |
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