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Methylglyoxal and glyoxalase 1—a metabolic stress pathway-linking hyperglycemia to the unfolded protein response and vascular complications of diabetes
The study of the glyoxalase system by Thornalley and co-workers in clinical diabetes mellitus and correlation with diabetic complications revealed increased exposure of patients with diabetes to the reactive, dicarbonyl metabolite methylglyoxal (MG). Twenty-eight years later, extended and built on b...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152679/ https://www.ncbi.nlm.nih.gov/pubmed/35635155 http://dx.doi.org/10.1042/CS20220099 |