Identification of the target and mode of action for the prokaryotic nucleotide excision repair inhibitor ATBC

In bacteria, nucleotide excision repair (NER) plays a major role in repairing DNA damage from a wide variety of sources. Therefore, its inhibition offers potential to develop a new antibacterial in combination with adjuvants, such as UV light. To date, only one known chemical inhibitor of NER is 2-(...

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Detalles Bibliográficos
Autores principales: Bernacchia, Lorenzo, Paris, Antoine, Gupta, Arya, Moores, Alexandra A., Kad, Neil M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Enzymology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152706/
https://www.ncbi.nlm.nih.gov/pubmed/35546304
http://dx.doi.org/10.1042/BSR20220403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152706/
https://www.ncbi.nlm.nih.gov/pubmed/35546304
http://dx.doi.org/10.1042/BSR20220403

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