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Identification of the target and mode of action for the prokaryotic nucleotide excision repair inhibitor ATBC
In bacteria, nucleotide excision repair (NER) plays a major role in repairing DNA damage from a wide variety of sources. Therefore, its inhibition offers potential to develop a new antibacterial in combination with adjuvants, such as UV light. To date, only one known chemical inhibitor of NER is 2-(...
Autores principales: | Bernacchia, Lorenzo, Paris, Antoine, Gupta, Arya, Moores, Alexandra A., Kad, Neil M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152706/ https://www.ncbi.nlm.nih.gov/pubmed/35546304 http://dx.doi.org/10.1042/BSR20220403 |
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