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Profound systemic alteration of the immune phenotype and an immunoglobulin switch in Erdheim-Chester disease in 78 patients from a single center

Erdheim-Chester disease (ECD) is a rare, systemic, non-Langerhans cell histiocytosis neoplasm, which is characterized by the infiltration of CD63(+) CD1a(-) histiocytes in multiple tissues. The BRAF(V600E) mutation is frequently present in individuals with ECD and has been detected in hematopoietic...

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Detalles Bibliográficos
Autores principales: Aubart, Fleur Cohen, Poupel, Lucie, Saint-Charles, Flora, Charlotte, Frédéric, Arsafi, Youssef, Frisdal, Eric, Roos-Weil, Damien, Emile, Jean-François, Amoura, Zahir, Guerin, Maryse, Lesnik, Philippe, Haroche, Julien, Le Goff, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152974/
https://www.ncbi.nlm.nih.gov/pubmed/34647443
http://dx.doi.org/10.3324/haematol.2021.279118