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Distinct clinical characteristics of DUX4- and PAX5-altered childhood B-lymphoblastic leukemia

Among the recently described subtypes in childhood B-lymphoblastic leukemia (B-ALL) were DUX4- and PAX5-altered (PAX5alt). By using whole transcriptome RNA sequencing in 377 children with B-ALL from the Malaysia-Singapore ALL 2003 (MS2003) and Malaysia-Singapore ALL 2010 (MS2010) studies, we found t...

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Detalles Bibliográficos
Autores principales: Li, Zhenhua, Lee, Shawn Hsien Ren, Chin, Winnie Hui Ni, Lu, Yi, Jiang, Nan, Lim, Evelyn Huizi, Coustan-Smith, Elaine, Chiew, Kean Hui, Oh, Bernice Ling Zhi, Koh, Grace Shimin, Chen, Zhiwei, Kham, Shirley Kow Yin, Quah, Thuan Chong, Lin, Hai Peng, Tan, Ah Moy, Ariffin, Hany, Yang, Jun J., Yeoh, Allen Eng-Juh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9152998/
https://www.ncbi.nlm.nih.gov/pubmed/34547766
http://dx.doi.org/10.1182/bloodadvances.2021004895