Platelet FcγRIIA-induced serotonin release exacerbates the severity of transfusion-related acute lung injury in mice

Transfusion-related acute lung injury (TRALI) remains a major cause of transfusion-related fatalities. The mechanism of human antibody-mediated TRALI, especially the involvement of the Fcγ receptors, is not clearly established. Contrary to mice, human platelets are unique in their expression of the...

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Detalles Bibliográficos
Autores principales: El Mdawar, Marie-Belle, Maître, Blandine, Magnenat, Stéphanie, Tupin, Florian, Jönsson, Friederike, Gachet, Christian, de la Salle, Henri, Hechler, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153039/
https://www.ncbi.nlm.nih.gov/pubmed/34521102
http://dx.doi.org/10.1182/bloodadvances.2021004336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153039/
https://www.ncbi.nlm.nih.gov/pubmed/34521102
http://dx.doi.org/10.1182/bloodadvances.2021004336

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