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Platelet FcγRIIA-induced serotonin release exacerbates the severity of transfusion-related acute lung injury in mice
Transfusion-related acute lung injury (TRALI) remains a major cause of transfusion-related fatalities. The mechanism of human antibody-mediated TRALI, especially the involvement of the Fcγ receptors, is not clearly established. Contrary to mice, human platelets are unique in their expression of the...
Autores principales: | El Mdawar, Marie-Belle, Maître, Blandine, Magnenat, Stéphanie, Tupin, Florian, Jönsson, Friederike, Gachet, Christian, de la Salle, Henri, Hechler, Beatrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153039/ https://www.ncbi.nlm.nih.gov/pubmed/34521102 http://dx.doi.org/10.1182/bloodadvances.2021004336 |
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