Anti-inflammatory treatment in MPN: targeting TNFR1 and TNFR2 in JAK2-V617F–induced disease

Chronic nonresolving inflammatory syndrome is a major disease feature in myeloproliferative neoplasms (MPNs). Systemic inflammation promotes the growth of the JAK2-V617F(+) hematopoietic stem cell clone and is associated with constitutive symptoms (eg, fever, cachexia, and fatigue). Therefore, it is...

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Detalles Bibliográficos
Autores principales: Müller, Peter, Baldauf, Conny K., Haage, Tobias R., Waldleben, Ana M., Richter, Fabian, Pfizenmaier, Klaus, Fischer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153051/
https://www.ncbi.nlm.nih.gov/pubmed/34592754
http://dx.doi.org/10.1182/bloodadvances.2021004438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153051/
https://www.ncbi.nlm.nih.gov/pubmed/34592754
http://dx.doi.org/10.1182/bloodadvances.2021004438

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