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Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance
BACKGROUND: Vascular dementia (VAD) is the second most common type of dementia lacking effective treatments. Pentoxifylline (PTX), a nonselective phosphodiesterase inhibitor, displays protective effects in multiple cerebral diseases. In this study, we aimed to investigate the therapeutic effects and...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153105/ https://www.ncbi.nlm.nih.gov/pubmed/35642056 http://dx.doi.org/10.1186/s12974-022-02480-4 |