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Mxc, a Drosophila homolog of mental retardation-associated gene NPAT, maintains neural stem cell fate

BACKGROUND: Mental retardation is a complex neurodevelopmental disorder. NPAT, a component of the histone locus body (HLB), has been implicated as a candidate gene for mental retardation, with a mechanism yet to be elucidated. RESULTS: We identified that mxc, the Drosophila ortholog of NPAT, is requ...

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Detalles Bibliográficos
Autores principales: Sang, Rong, Wu, Cheng, Xie, Shanshan, Xu, Xiao, Lou, Yuhan, Ge, Wanzhong, Xi, Yongmei, Yang, Xiaohang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153134/
https://www.ncbi.nlm.nih.gov/pubmed/35642004
http://dx.doi.org/10.1186/s13578-022-00820-8