Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer

BACKGROUND: Platinum based agents—cisplatin and carboplatin in combination with taxanes are used for the treatment of ovarian cancer (OC) patients. However, the majority of OC patients develop recurrent, platinum resistant disease that is uniformly fatal. Platinum treatment enriches for chemoresista...

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Detalles Bibliográficos
Autores principales: Sriramkumar, Shruthi, Sood, Riddhi, Huntington, Thomas D., Ghobashi, Ahmed H., Vuong, Truc T., Metcalfe, Tara X., Wang, Weini, Nephew, Kenneth P., O’Hagan, Heather M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153190/
https://www.ncbi.nlm.nih.gov/pubmed/35641987
http://dx.doi.org/10.1186/s12967-022-03447-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153190/
https://www.ncbi.nlm.nih.gov/pubmed/35641987
http://dx.doi.org/10.1186/s12967-022-03447-y

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