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Efficient automatic 3D segmentation of cell nuclei for high-content screening

BACKGROUND: High-content screening (HCS) is a pre-clinical approach for the assessment of drug efficacy. On modern platforms, it involves fluorescent image capture using three-dimensional (3D) scanning microscopy. Segmentation of cell nuclei in 3D images is an essential prerequisite to quantify capt...

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Detalles Bibliográficos
Autores principales: Marzec, Mariusz, Piórkowski, Adam, Gertych, Arkadiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153210/
https://www.ncbi.nlm.nih.gov/pubmed/35641922
http://dx.doi.org/10.1186/s12859-022-04737-4