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Drug-induced CYP induction as therapy for tacrolimus intoxication

Management of calcineurin inhibitor (CNI) therapy in kidney transplant recipients may be complicated due to polypharmacy. As CNI undergo extensive metabolism by cytochrome-P450 enzymes (CYP), drug-mediated CYP inhibition poses a risk for elevated CNI blood concentrations. Here, we report on 2 kidney...

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Detalles Bibliográficos
Autores principales: Hoppe, John M., Holderied, Alexander, Schönermarck, Ulf, Vielhauer, Volker, Anders, Hans-Joachim , Fischereder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9153279/
https://www.ncbi.nlm.nih.gov/pubmed/35651717
http://dx.doi.org/10.5414/CNCS110744