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Local chromatin context regulates the genetic requirements of the heterochromatin spreading reaction
Heterochromatin spreading, the expansion of repressive chromatin structure from sequence-specific nucleation sites, is critical for stable gene silencing. Spreading re-establishes gene-poor constitutive heterochromatin across cell cycles but can also invade gene-rich euchromatin de novo to steer cel...
Autores principales: | Greenstein, R. A., Ng, Henry, Barrales, Ramon R., Tan, Catherine, Braun, Sigurd, Al-Sady, Bassem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154106/ https://www.ncbi.nlm.nih.gov/pubmed/35584134 http://dx.doi.org/10.1371/journal.pgen.1010201 |
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