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Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity

Pseudorabies virus (PRV) has evolved various immune evasion mechanisms that target host antiviral immune responses. However, it is unclear whether and how PRV encoded proteins modulate the cGAS-STING axis for immune evasion. Here, we show that PRV tegument protein UL13 inhibits STING-mediated antivi...

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Detalles Bibliográficos
Autores principales: Kong, Zhengjie, Yin, Hongyan, Wang, Fan, Liu, Zhen, Luan, Xiaohan, Sun, Lei, Liu, Wenjun, Shang, Yingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154183/
https://www.ncbi.nlm.nih.gov/pubmed/35584187
http://dx.doi.org/10.1371/journal.ppat.1010544