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Fat and exposure to 4-nitroquinoline-1-oxide causes histologic and inflammatory changes in murine livers

Risk factors for liver cancer include tobacco use, alcohol consumption, obesity, and male sex. Administration of 4-nitroquinonline-1-oxide (4NQO) in drinking water mimics the effects of tobacco and leads to oral carcinoma in mice. This study compared the effects of diets high and low in saturated fa...

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Detalles Bibliográficos
Autores principales: Pitstick, Lenore D., Goral, Joanna, Schmelter, Ryan A., Fuja, Christine M., Ciancio, Mae J., Pytynia, Matthew, Meyer, Alice, Green, Jacalyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154184/
https://www.ncbi.nlm.nih.gov/pubmed/35639668
http://dx.doi.org/10.1371/journal.pone.0268891