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Fat and exposure to 4-nitroquinoline-1-oxide causes histologic and inflammatory changes in murine livers
Risk factors for liver cancer include tobacco use, alcohol consumption, obesity, and male sex. Administration of 4-nitroquinonline-1-oxide (4NQO) in drinking water mimics the effects of tobacco and leads to oral carcinoma in mice. This study compared the effects of diets high and low in saturated fa...
Autores principales: | Pitstick, Lenore D., Goral, Joanna, Schmelter, Ryan A., Fuja, Christine M., Ciancio, Mae J., Pytynia, Matthew, Meyer, Alice, Green, Jacalyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154184/ https://www.ncbi.nlm.nih.gov/pubmed/35639668 http://dx.doi.org/10.1371/journal.pone.0268891 |
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