Spatially resolved in silico modeling of NKG2D signaling kinetics suggests a key role of NKG2D and Vav1 Co-clustering in generating natural killer cell activation

Natural Killer (NK) cells provide key resistance against viral infections and tumors. A diverse set of activating and inhibitory NK cell receptors (NKRs) interact with cognate ligands presented by target host cells, where integration of dueling signals initiated by the ligand-NKR interactions determ...

Descripción completa

Detalles Bibliográficos
Autores principales: Grewal, Rajdeep Kaur, Das, Jayajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154193/
https://www.ncbi.nlm.nih.gov/pubmed/35584138
http://dx.doi.org/10.1371/journal.pcbi.1010114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154193/
https://www.ncbi.nlm.nih.gov/pubmed/35584138
http://dx.doi.org/10.1371/journal.pcbi.1010114

Ejemplares similares