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Effect of Glucocorticoid and 11β-Hydroxysteroid-Dehydrogenase Type 1 (11β-HSD1) in Neurological and Psychiatric Disorders

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) activity is implicated as a moderator of the progression of multiple diseases and disorders in medicine and is actively subject to investigation as a therapeutic target. Here we summarize the mechanisms of the enzyme and detail the novel agents unde...

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Detalles Bibliográficos
Autores principales: Dodd, Seetal, Skvarc, David R, Dean, Olivia M, Anderson, Anna, Kotowicz, Mark, Berk, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154221/
https://www.ncbi.nlm.nih.gov/pubmed/35143668
http://dx.doi.org/10.1093/ijnp/pyac014