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DRUMMER—rapid detection of RNA modifications through comparative nanopore sequencing

MOTIVATION: The chemical modification of ribonucleotides regulates the structure, stability and interactions of RNAs. Profiling of these modifications using short-read (Illumina) sequencing techniques provides high sensitivity but low-to-medium resolution i.e. modifications cannot be assigned to spe...

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Detalles Bibliográficos
Autores principales: Abebe, Jonathan S, Price, Alexander M, Hayer, Katharina E, Mohr, Ian, Weitzman, Matthew D, Wilson, Angus C, Depledge, Daniel P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154255/
https://www.ncbi.nlm.nih.gov/pubmed/35426900
http://dx.doi.org/10.1093/bioinformatics/btac274