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deepSimDEF: deep neural embeddings of gene products and gene ontology terms for functional analysis of genes

MOTIVATION: There is a plethora of measures to evaluate functional similarity (FS) of genes based on their co-expression, protein–protein interactions and sequence similarity. These measures are typically derived from hand-engineered and application-specific metrics to quantify the degree of shared...

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Detalles Bibliográficos
Autores principales: Pesaranghader, Ahmad, Matwin, Stan, Sokolova, Marina, Grenier, Jean-Christophe, Beiko, Robert G, Hussin, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154256/
https://www.ncbi.nlm.nih.gov/pubmed/35536192
http://dx.doi.org/10.1093/bioinformatics/btac304