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MHC class II molecules on pancreatic cancer cells indicate a potential for neo-antigen-based immunotherapy

MHC class II expression is a hallmark of professional antigen-presenting cells and key to the induction of CD4+ T helper cells. We found that these molecules are ectopically expressed on tumor cells in a large proportion of patients with pancreatic ductal adenocarcinoma (PDAC) and on several PDAC ce...

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Detalles Bibliográficos
Autores principales: Baleeiro, Renato B., Bouwens, Christian J., Liu, Peng, Di Gioia, Carmela, Dunmall, Louisa S. Chard, Nagano, Ai, Gangeswaran, Rathistevy, Chelala, Claude, Kocher, Hemant M., Lemoine, Nicholas R., Wang, Yaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154752/
https://www.ncbi.nlm.nih.gov/pubmed/35655709
http://dx.doi.org/10.1080/2162402X.2022.2080329