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Alpinetin suppresses CYP3A4, 2C9, and 2E1 activity in vitro

CONTEXT: Alpinetin, the major active constitutes of Alpinia katsumata Hayata (Zingiberaceae), has been demonstrated to possess the activity of anti-breast cancer. Cytochrome P450 enzymes (CYP450s) plays vital roles in the biotransformation of various drugs. OBJECTIVE: To assess the effect of alpinet...

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Detalles Bibliográficos
Autores principales: Song, Hongming, Wei, Chuankui, Yang, Wu, Niu, Zhaohe, Gong, Mingkai, Hu, Haiyan, Wang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154758/
https://www.ncbi.nlm.nih.gov/pubmed/35634649
http://dx.doi.org/10.1080/13880209.2022.2071450