Selective inhibition of carbonic anhydrase IX by sulphonylated 1,2,3-triazole incorporated benzenesulphonamides capable of inducing apoptosis

In search of selective carbonic anhydrase (CA) IX inhibitors endowed with apoptotic inducing properties, we designed and synthesised two subsets of 4- and 3-(5-aryl-(4-phenylsulphonyl)-1H-1,2,3-triazol-1-yl)benzenesulphonamides. All compounds were assayed for human carbonic anhydrase (hCA) isoforms...

Descripción completa

Detalles Bibliográficos
Autores principales: Siwach, Kiran, Kumar, Amit, Panchal, Harish, Kumar, Rajiv, Bhardwaj, Jitender Kumar, Angeli, Andrea, Supuran, Claudiu T., Sharma, Pawan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154810/
https://www.ncbi.nlm.nih.gov/pubmed/35616287
http://dx.doi.org/10.1080/14756366.2022.2077333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154810/
https://www.ncbi.nlm.nih.gov/pubmed/35616287
http://dx.doi.org/10.1080/14756366.2022.2077333

Ejemplares similares