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Selective inhibition of carbonic anhydrase IX by sulphonylated 1,2,3-triazole incorporated benzenesulphonamides capable of inducing apoptosis

In search of selective carbonic anhydrase (CA) IX inhibitors endowed with apoptotic inducing properties, we designed and synthesised two subsets of 4- and 3-(5-aryl-(4-phenylsulphonyl)-1H-1,2,3-triazol-1-yl)benzenesulphonamides. All compounds were assayed for human carbonic anhydrase (hCA) isoforms...

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Detalles Bibliográficos
Autores principales:	Siwach, Kiran, Kumar, Amit, Panchal, Harish, Kumar, Rajiv, Bhardwaj, Jitender Kumar, Angeli, Andrea, Supuran, Claudiu T., Sharma, Pawan K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154810/ https://www.ncbi.nlm.nih.gov/pubmed/35616287 http://dx.doi.org/10.1080/14756366.2022.2077333

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