Population pharmacokinetics of intravenous cefotaxime indicates that higher doses are required for critically ill children

BACKGROUND: Cefotaxime is frequently used in critically ill children, however pharmacokinetic (PK) studies to support adequate dosing in this patient population are limited. OBJECTIVES: To characterize cefotaxime PK in critically ill children and evaluate exposures achieved by current and alternativ...

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Detalles Bibliográficos
Autores principales: Hartman, Stan J. F., Upadhyay, Parth J., Mathôt, Ron A. A., van der Flier, Michiel, Schreuder, Michiel F., Brüggemann, Roger J., Knibbe, Catherijne A., de Wildt, Saskia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155601/
https://www.ncbi.nlm.nih.gov/pubmed/35383374
http://dx.doi.org/10.1093/jac/dkac095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155601/
https://www.ncbi.nlm.nih.gov/pubmed/35383374
http://dx.doi.org/10.1093/jac/dkac095

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