Omadacycline efficacy in the hollow fibre system model of pulmonary Mycobacterium avium complex and potency at clinically attainable doses

OBJECTIVES: The standard of care (SOC) for the treatment of pulmonary Mycobacterium avium complex (MAC) disease (clarithromycin, rifabutin, and ethambutol) achieves sustained sputum conversion rates of only 54%. Thus, new treatments should be prioritized. METHODS: We identified the omadacycline MIC...

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Detalles Bibliográficos
Autores principales: Chapagain, Moti, Pasipanodya, Jotam G., Athale, Shruti, Bernal, Claude, Trammell, Rachel, Howe, David, Gumbo, Tawanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155607/
https://www.ncbi.nlm.nih.gov/pubmed/35257162
http://dx.doi.org/10.1093/jac/dkac068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155607/
https://www.ncbi.nlm.nih.gov/pubmed/35257162
http://dx.doi.org/10.1093/jac/dkac068

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