Idol Depletion Protects against Spontaneous Atherosclerosis in a Hamster Model of Familial Hypercholesterolemia

Inducible degrader of low-density lipoprotein (LDL) receptor (Idol) is an E3 ubiquitin ligase coded by Idol, the target gene of liver X receptor (LXR), which primarily mediates the ubiquitination and lysosomal degradation of low-density lipoprotein receptor (LDLR). Previous studies from independent...

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Detalles Bibliográficos
Autores principales: Liang, Chenxi, Wang, Xiaowei, Peng, Kenan, Lai, Pingping, Liu, Ziwei, Ma, Jiaao, Chen, Xin, Liu, Gang, Zheng, Mingqi, Wang, Yuhui, Yang, Hongyuan, Liu, George, Xian, Xunde, Gao, Mingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155911/
https://www.ncbi.nlm.nih.gov/pubmed/35656026
http://dx.doi.org/10.1155/2022/1889632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155911/
https://www.ncbi.nlm.nih.gov/pubmed/35656026
http://dx.doi.org/10.1155/2022/1889632

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