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Idol Depletion Protects against Spontaneous Atherosclerosis in a Hamster Model of Familial Hypercholesterolemia
Inducible degrader of low-density lipoprotein (LDL) receptor (Idol) is an E3 ubiquitin ligase coded by Idol, the target gene of liver X receptor (LXR), which primarily mediates the ubiquitination and lysosomal degradation of low-density lipoprotein receptor (LDLR). Previous studies from independent...
Autores principales: | Liang, Chenxi, Wang, Xiaowei, Peng, Kenan, Lai, Pingping, Liu, Ziwei, Ma, Jiaao, Chen, Xin, Liu, Gang, Zheng, Mingqi, Wang, Yuhui, Yang, Hongyuan, Liu, George, Xian, Xunde, Gao, Mingming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9155911/ https://www.ncbi.nlm.nih.gov/pubmed/35656026 http://dx.doi.org/10.1155/2022/1889632 |
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