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Epistasis Creates Invariant Sites and Modulates the Rate of Molecular Evolution

Invariant sites are a common feature of amino acid sequence evolution. The presence of invariant sites is frequently attributed to the need to preserve function through site-specific conservation of amino acid residues. Amino acid substitution models without a provision for invariant sites often fit...

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Detalles Bibliográficos
Autores principales: Patel, Ravi, Carnevale, Vincenzo, Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156017/
https://www.ncbi.nlm.nih.gov/pubmed/35575390
http://dx.doi.org/10.1093/molbev/msac106