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Epistasis Creates Invariant Sites and Modulates the Rate of Molecular Evolution
Invariant sites are a common feature of amino acid sequence evolution. The presence of invariant sites is frequently attributed to the need to preserve function through site-specific conservation of amino acid residues. Amino acid substitution models without a provision for invariant sites often fit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156017/ https://www.ncbi.nlm.nih.gov/pubmed/35575390 http://dx.doi.org/10.1093/molbev/msac106 |