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Blood DNA methylation at TXNIP and glycemic changes in response to weight-loss diet interventions: the POUNDS Lost Trial
BACKGROUND: Thioredoxin Interacting Protein (TXNIP) functions as a master regulator for glucose homeostasis. Hypomethylation at the 5’-cytosine-phosphate-guanine-3’ (CpG) site cg19693031 of TXNIP has been consistently related to islet dysfunction, hyperglycemia, and type 2 diabetes. DNA methylation...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156542/ https://www.ncbi.nlm.nih.gov/pubmed/35165382 http://dx.doi.org/10.1038/s41366-022-01084-5 |