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Omega-3 fatty acid epoxides produced by PAF-AH2 in mast cells regulate pulmonary vascular remodeling
Pulmonary hypertension is a fatal rare disease that causes right heart failure by elevated pulmonary arterial resistance. There is an unmet medical need for the development of therapeutics focusing on the pulmonary vascular remodeling. Bioactive lipids produced by perivascular inflammatory cells mig...
Autores principales: | Moriyama, Hidenori, Endo, Jin, Kataoka, Masaharu, Shimanaka, Yuta, Kono, Nozomu, Sugiura, Yuki, Goto, Shinichi, Kitakata, Hiroki, Hiraide, Takahiro, Yoshida, Naohiro, Isobe, Sarasa, Yamamoto, Tsunehisa, Shirakawa, Kohsuke, Anzai, Atsushi, Katsumata, Yoshinori, Suematsu, Makoto, Kosaki, Kenjiro, Fukuda, Keiichi, Arai, Hiroyuki, Sano, Motoaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156667/ https://www.ncbi.nlm.nih.gov/pubmed/35641514 http://dx.doi.org/10.1038/s41467-022-30621-z |
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