Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

Repeated direct venous inoculation of Plasmodium falciparum sporozoites (PfSPZ) together with antimalarial chemoprophylaxis (PfSPZ–CVac) is the most potent way to induce sterile immunity against P. falciparum infection in malaria-naive volunteers. However, established schedules are complex and long....

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Detalles Bibliográficos
Autores principales: Ibanez, Javier, Fendel, Rolf, Lorenz, Freia-Raphaella, Granados-Bayon, Patricia, Brückner, Sina, Esen, Meral, Sulyok, Mihály, Sulyok, Zita, Borrmann, Steffen, Bacher, Petra, Scheffold, Alexander, Hoffman, Stephen L., Kremsner, Peter G., Mordmüller, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156686/
https://www.ncbi.nlm.nih.gov/pubmed/35641527
http://dx.doi.org/10.1038/s41541-022-00473-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156686/
https://www.ncbi.nlm.nih.gov/pubmed/35641527
http://dx.doi.org/10.1038/s41541-022-00473-1

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