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Cellular engagement and interaction in the tumor microenvironment predict non-response to PD-1/PD-L1 inhibitors in metastatic non-small cell lung cancer

Immune checkpoint inhibitors (ICI) with anti-PD-1/PD-L1 agents have improved the survival of patients with metastatic non-small cell lung cancer (mNSCLC). Tumor PD-L1 expression is an imperfect biomarker as it does not capture the complex interactions between constituents of the tumor microenvironme...

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Detalles Bibliográficos
Autores principales: Qin, Angel, Lima, Fatima, Bell, Samantha, Kalemkerian, Gregory P., Schneider, Bryan J., Ramnath, Nithya, Lew, Madelyn, Krishnan, Santhoshi, Mohammed, Shariq, Rao, Arvind, Frankel, Timothy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156701/
https://www.ncbi.nlm.nih.gov/pubmed/35641540
http://dx.doi.org/10.1038/s41598-022-13236-8