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Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity

Biomolecular condensates require suitable control of material properties for their function. Here we apply Differential Dynamic Microscopy (DDM) to probe the material properties of an in vitro model of processing bodies consisting of out-of-equilibrium condensates formed by the DEAD-box ATPase Dhh1...

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Detalles Bibliográficos
Autores principales: Linsenmeier, Miriam, Hondele, Maria, Grigolato, Fulvio, Secchi, Eleonora, Weis, Karsten, Arosio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156751/
https://www.ncbi.nlm.nih.gov/pubmed/35641495
http://dx.doi.org/10.1038/s41467-022-30521-2