Cargando…
Dynamic arrest and aging of biomolecular condensates are modulated by low-complexity domains, RNA and biochemical activity
Biomolecular condensates require suitable control of material properties for their function. Here we apply Differential Dynamic Microscopy (DDM) to probe the material properties of an in vitro model of processing bodies consisting of out-of-equilibrium condensates formed by the DEAD-box ATPase Dhh1...
Autores principales: | Linsenmeier, Miriam, Hondele, Maria, Grigolato, Fulvio, Secchi, Eleonora, Weis, Karsten, Arosio, Paolo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156751/ https://www.ncbi.nlm.nih.gov/pubmed/35641495 http://dx.doi.org/10.1038/s41467-022-30521-2 |
Ejemplares similares
-
Sequestration within biomolecular condensates inhibits Aβ-42 amyloid formation
por: Küffner, Andreas M., et al.
Publicado: (2021) -
Pat1 promotes processing body assembly by enhancing the phase separation of the DEAD-box ATPase Dhh1 and RNA
por: Sachdev, Ruchika, et al.
Publicado: (2019) -
The interface of condensates of the hnRNPA1 low-complexity domain promotes formation of amyloid fibrils
por: Linsenmeier, Miriam, et al.
Publicado: (2023) -
Biomolecular condensates as arbiters of biochemical reactions inside the nucleus
por: Laflamme, Guillaume, et al.
Publicado: (2020) -
Wetting and complex remodeling of membranes by biomolecular condensates
por: Mangiarotti, Agustín, et al.
Publicado: (2023)