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Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes
Improved models of experimental diabetes are needed to develop cell therapies for diabetes. Here, we introduce the B6 RIP-DTR mouse, a model of experimental diabetes in fully immunocompetent animals. These inbred mice harbor the H2(b) major histocompatibility complex (MHC), selectively express high...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156753/ https://www.ncbi.nlm.nih.gov/pubmed/35641781 http://dx.doi.org/10.1038/s41598-022-13087-3 |