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Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure

Acute liver failure (ALF) is a rare entity but exhibits a high mortality. The mechanisms underlying ALF are not completely understood. The present study explored the role of the hepatic B cell leukemia-3 (Bcl-3), a transcriptional regulator of nuclear factor-kappa B (NF-κB), in two independent model...

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Detalles Bibliográficos
Autores principales: Gehrke, Nadine, Wörns, Marcus A., Mann, Amrit, Hövelmeyer, Nadine, Waisman, Ari, Straub, Beate K., Galle, Peter R., Schattenberg, Jörn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156769/
https://www.ncbi.nlm.nih.gov/pubmed/35641486
http://dx.doi.org/10.1038/s41419-022-04946-y