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Elucidating the molecular basis of spontaneous activation in an engineered mechanosensitive channel

Mechanosensitive channel of large conductance (MscL) detects and responds to changes in the pressure profile of cellular membranes and transduces the mechanical energy into electrical and/or chemical signals. MscL can be activated using ultrasonic or chemical activation methods to improve the absorp...

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Detalles Bibliográficos
Autores principales: Immadisetty, Kalyan, Polasa, Adithya, Shelton, Reid, Moradi, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156883/
https://www.ncbi.nlm.nih.gov/pubmed/35685356
http://dx.doi.org/10.1016/j.csbj.2022.05.022