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Cost-effective, green HPLC determination of losartan, valsartan and their nitrosodiethylamine impurity: application to pharmaceutical dosage forms

Angiotensin-converting enzyme inhibitors are one of the most widely used anti-hypertensive drugs which are used to reduce hypertension. In 2018, the United States Food and Drug Administration together with the European Medicine Agency declared the presence of carcinogenic nitrosamine impurities such...

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Detalles Bibliográficos
Autores principales: Abd El-Hay, Soad S., Elhenawee, Magda, Maged, Khaled, Ibrahim, Adel Ehab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9156911/
https://www.ncbi.nlm.nih.gov/pubmed/35706671
http://dx.doi.org/10.1098/rsos.220250