Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling

Aberrant activation or suppression of WNT/β-catenin signaling contributes to cancer initiation and progression, neurodegeneration, and bone disease. However, despite great need and more than 40 years of research, targeted therapies for the WNT pathway have yet to be fully realized. Kinases are consi...

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Detalles Bibliográficos
Autores principales: Agajanian, Megan J., Potjewyd, Frances M., Bowman, Brittany M., Solomon, Smaranda, LaPak, Kyle M., Bhatt, Dhaval P., Smith, Jeffery L., Goldfarb, Dennis, Axtman, Alison D., Major, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157009/
https://www.ncbi.nlm.nih.gov/pubmed/35487243
http://dx.doi.org/10.1016/j.jbc.2022.101986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157009/
https://www.ncbi.nlm.nih.gov/pubmed/35487243
http://dx.doi.org/10.1016/j.jbc.2022.101986

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