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A natural genetic variation screen identifies insulin signaling, neuronal communication, and innate immunity as modifiers of hyperglycemia in the absence of Sirt1

Variation in the onset, progression, and severity of symptoms associated with metabolic disorders such as diabetes impairs the diagnosis and treatment of at-risk patients. Diabetes symptoms, and patient variation in these symptoms, are attributed to a combination of genetic and environmental factors...

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Detalles Bibliográficos
Autores principales: Palu, Rebecca A S, Owings, Katie G, Garces, John G, Nicol, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157059/
https://www.ncbi.nlm.nih.gov/pubmed/35435227
http://dx.doi.org/10.1093/g3journal/jkac090