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Cas9-mediated maternal effect and derived resistance alleles in a gene-drive strain of the African malaria vector mosquito, Anopheles gambiae

CRISPR/Cas9 technologies are important tools for the development of gene-drive systems to modify mosquito vector populations to control the transmission of pathogens that cause diseases such as malaria. However, one of the challenges for current Cas9-based drive systems is their ability to produce d...

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Detalles Bibliográficos
Autores principales: Carballar-Lejarazú, Rebeca, Tushar, Taylor, Pham, Thai Binh, James, Anthony A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9157122/
https://www.ncbi.nlm.nih.gov/pubmed/35389492
http://dx.doi.org/10.1093/genetics/iyac055